Novel amperometric xanthine biosensor based on xanthine oxidase immobilized on electrochemically polymerized 10[4H-dithieno(3,2-b:2 ',3 '-d)pyrrole-4-yl] decane-1-amine film

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dc.authorid0000-0001-6492-6572en_US
dc.contributor.authorDervisevic, Muamer
dc.contributor.authorDervisevic, Esma
dc.contributor.authorAzak, Hacer
dc.contributor.authorÇevik, Emre
dc.contributor.authorSenel, Mehmet
dc.contributor.authorYıldız, Hüseyin Bekir
dc.date.accessioned2019-12-06T21:16:26Z
dc.date.available2019-12-06T21:16:26Z
dc.date.issued2016
dc.departmentKMÜ, Kamil Özdağ Fen Fakültesi, Kimya Bölümüen_US
dc.descriptionWOS:000366759500023en_US
dc.description.abstractIn this paper, a novel amperometric xanthine (X) biosensor is constructed by xanthine oxidase (XOx) immobilization on the pencil graphite electrode (PGE). Xanthine oxidase is immobilized using glutaraldehyde (GA) on the electrochemically polymerized conducting polymer film. The detection of xanthine is based on its consumed amount due to the enzymatic reaction of xanthine oxidase. The effects of polymer thickness, applied potential, pH, and temperature were investigated and optimum parameters were found to be five cycles, +5V, +0.5V and 30 degrees C, respectively. Storage stability, operation stability of the enzyme electrode, and effect of interferant substances on the amperometric response were also studied. In order to verify the applicability of proposed biosensor, fabricated electrode was used to measure the xanthine concentration in chicken meat samples. The present xanthine biosensor with high selectivity, sensitivity, and stability is promising for practical applications. (C) 2015 Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [111T135]; Scientific Research Projects Foundation of Karamanoglu Mehmetbey University (KMU-BAP)Karamanoglu Mehmetbey University [02-D-13]en_US
dc.description.sponsorshipThis study was supported financially by the Scientific and Technological Research Council of Turkey (TUBITAK Grant Number 111T135) and the Scientific Research Projects Foundation of Karamanoglu Mehmetbey University (KMU-BAP Grant Number 02-D-13).en_US
dc.identifier.citationDervisevic, M., Dervisevic, E., Azak, H., Çevik, E., Şenel, M., Yıldız, H. B. (2016). Novel amperometric xanthine biosensor based on xanthine oxidase immobilized on electrochemically polymerized 10-[4H-dithieno(3,2-b:2′,3′-d)pyrrole-4-yl]decane-1-amine film. Sensors and Actuators B: Chemical, 225, 181-187
dc.identifier.doi10.1016/j.snb.2015.11.043
dc.identifier.endpage187en_US
dc.identifier.issn0925-4005
dc.identifier.scopus2-s2.0-84947975941
dc.identifier.scopusqualityQ1
dc.identifier.startpage181en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.snb.2015.11.043
dc.identifier.urihttps://hdl.handle.net/11492/2902
dc.identifier.volume225en_US
dc.identifier.wosWOS:000366759500023
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Sceince
dc.indekslendigikaynakScopus
dc.institutionauthorAzak, Hacer
dc.language.isoen
dc.publisherElsevier Science SAen_US
dc.relation.journalSensors and Actuators B-Chemicalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAmperometryen_US
dc.subjectXanthine Oxidaseen_US
dc.subjectConducting Polymeren_US
dc.subjectBiosensoren_US
dc.titleNovel amperometric xanthine biosensor based on xanthine oxidase immobilized on electrochemically polymerized 10[4H-dithieno(3,2-b:2 ',3 '-d)pyrrole-4-yl] decane-1-amine filmen_US
dc.typeArticle

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