Investigation of phenolic composition, antioxidant capacity, and antidiabetic effect of ornithogalum Lanceolatum L.: An in vitro Study

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dc.authorid0000-0002-4680-3023en_US
dc.contributor.authorTemiz, Mehmet Ali
dc.date.accessioned2021-08-24T11:47:43Z
dc.date.available2021-08-24T11:47:43Z
dc.date.issued2021en_US
dc.departmentKMÜ, Teknik Bilimler Meslek Yüksekokulu, Bitkisel ve Hayvansal Üretim Bölümüen_US
dc.description.abstractDiabetes Mellitus is a global health problem that leads to macro- and microvascular diseases associated with hyperglycemia. Phytotherapy is one of the alternative ways to cope with this type of disease. The genus Ornithogalum is consumed as a wild edible plant and traditionally used for ailments. This study aims to investigate the phenolic composition using High-Performance Liquid Chromatography as well as antioxidant and antidiabetic effects using spectrophotometric method of Ornithogalum lanceolatum L. aerial parts and bulb. In order to determine the antioxidant capacity total phenolic content, total flavonoid content and DPPH and ABTS free radical scavenging activities were analyzed in O. lanceolatum. Moreover, in vitro inhibitory effects of the O. lanceolatum aerial parts and bulb on digestive enzymes were determined by evaluating the α-amylase and α-glucosidase activities. Protocatechuic acid was found to be the main compound in both plant parts. However, the amounts of the total phenolic acids and flavonoids were found higher in the aerial parts than those in bulb as well. Furthermore, O. lanceolatum aerial parts exhibited more radical scavenging activity than bulb. The α-amylase and α-glucosidase IC50 inhibition activities of aerial parts were found more efficient than those for bulb. It can be concluded that O. lanceolatum can enhance the antioxidant status and also can prevent nutraceutically postprandial hyperglycemia by inhibiting α-amylase and α-glucosidase enzymes. These findings reveal the importance of traditional remedies in the ethnopharmacological use of herbs.en_US
dc.identifier.citationTemiz, M. A. (2021). Investigation of phenolic composition, antioxidant capacity, and antidiabetic effect of ornithogalum lanceolatum L.: An in vitro study. International Journal of Secondary Metabolite, 8(2), 94-103.en_US
dc.identifier.doi10.21448/ijsm.861904
dc.identifier.endpage103en_US
dc.identifier.issn2148-6905
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85110987741
dc.identifier.scopusqualityQ3
dc.identifier.startpage94en_US
dc.identifier.trdizinid1148167
dc.identifier.urihttps://hdl.handle.net/11492/5197
dc.identifier.volume8en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorTemiz, Mehmet Ali
dc.language.isoen
dc.publisherPamukkale Üniversitesien_US
dc.relation.journalInternational Journal of Secondary Metaboliteen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectABTSen_US
dc.subjectAntidiabeticen_US
dc.subjectα-glucosidaseen_US
dc.subjectDPPHen_US
dc.subjectOrnithogalum Lanceolatumen_US
dc.titleInvestigation of phenolic composition, antioxidant capacity, and antidiabetic effect of ornithogalum Lanceolatum L.: An in vitro Studyen_US
dc.typeArticle

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