Alterations in liver gene expression profile in streptozotocin-induced diabetic rats
Yükleniyor...
Tarih
2014
Yazarlar
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Dergi ISSN
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Yayıncı Yok
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Microarray technology has been applied to study the genomewide gene expression levels in streptozotocin (STZ) induced diabetic liver tissues, which plays a key role in glucose metabolism and homeostasis. The rats were fed with a standard diet and were randomly divided into two groups: (1) non-diabetic control group (2) diabetic group received STZ (55 mg/kg). After STZ injection, rats whose blood glucose concentration above 300 mg/ dl was considered as diabetic. After four weeks of diabetes, rats were decapitated and liver tissues were removed for microarray analysis.
Açıklama
Anahtar Kelimeler
Diabetes, Microarray, Gene expression
Kaynak
WoS Q Değeri
Q2
Scopus Q Değeri
Cilt
Sayı
Künye
Sadi, G.,Baloğlu, M.C."Alterations in liver gene expression profile in streptozotocin-induced diabetic rats" FEBS Journal,281,2014.
