An ultrasensitive ″OFF–ON″ fluorogenic sensor based on thiazole derivative for Zn2+: Food supplement, water and bio–imaging applications
Yükleniyor...
Dosyalar
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In the present study, the design of a novel turn–on fluorescent probe ((E)–5–methoxy–4–((thiazol–2–ylimino)methyl)benzene–1,3–diol) (TBD) was reported. TBD showed an excellent fluorogenic response (λex = 420 nm, λem = 530 nm) to sense Zn2+ in HEPES buffer/MeCN (5/95, v/v; pH = 7.4) media. The quantum (Φ) yield of the probe TBD increased importantly with Zn2+ and was calculated for TBD (Φ = 0.073) and TBD–Zn2+ complex (Φ = 0.78). The LOD and binding constant (Ka) of TBD were 1.29 nM and 1.102 × 106 M−1, respectively. The sensing process of TBD toward Zn2+ (1:1) was verified by the Job's plot, MALDI–TOF–MS, and 1H NMR titration studies. The ''off–on'' fluorogenic response of TBD was qualified to the photo–induced electron transfer (PET) process. The experimental outcomes were also verified by theoretical DFT studies. Furthermore, TBD had been successfully utilized to detect Zn2+ in food supplement products, drinkable water samples and living–cells for on–site analysis.
Açıklama
WOS:000687587600002
Anahtar Kelimeler
Zinc, Fluorescence Sensor, Thiazol, Water, Food Supplement, Living−cell
Kaynak
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
419
Sayı
Künye
Aydın, D., Karuk Elmas, S. N., Savran, T., Arslan, F. N., Sadi, G., Yılmaz, I. (2021). An ultrasensitive ″OFF–ON″ fluorogenic sensor based on thiazole derivative for Zn2+: Food supplement, water and bio–imaging applications. Journal of Photochemistry and Photobiology A: Chemistry, 419.
