Left and right ventricular function by echocardiography, tissue doppler imaging, carotid intima media thickness, and asymmetric dimethylarginine levels in female adolescents with vitamin D deficiency

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Tarih

2023

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Cambridge University Press

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Background: The aim of our study was to assess left and right ventricle systolic and diastolic functions in female adolescents with vitamin D deficiency using conventional echocardiography and pulsed-wave tissue Doppler imaging and to investigate carotid intima media thickness and asymmetric dimethylarginine levels. Methods: Sixty-six female adolescents were enrolled in this study. The female adolescents were divided into a vitamin D deficiency group (n: 34) and a control group (n: 32). All subjects underwent laboratory blood tests, including asymmetric dimethyl arginine, complete two-dimensional, pulse, and tissue Doppler echocardiography, and measurement of the carotid intima-media thickness. Results: The vitamin D-deficient female adolescent group had normal left and right ventricle systolic and diastolic functions and normal global systolic and diastolic myocardial performance. In the patients with vitamin D deficiency, the carotid intima-media thickness was higher than that in the controls. In the patients within the vitamin D deficiency group, vitamin D was found to be positively correlated with magnesium and negatively correlated with phosphorus and left atrial dimension. Conclusions: The results of this study demonstrate that vitamin D deficiency in female adolescence is associated with normal myocardial geometry and function. Although it has been associated with normal levels of asymmetric dimethyl arginine concentration, high measured carotid intima-media thickness may reflect endothelial dysfunction.

Açıklama

PMID: 37226488
WOS:001005936500001

Anahtar Kelimeler

Adolescent, Asymmetric Dimethyl Arginine, Cardiovascular Disease, Carotid Intima Media Thickness, Vitamin D Deficiency

Kaynak

WoS Q Değeri

Q3

Scopus Q Değeri

Q3

Cilt

Sayı

Künye

Aslan, E., Sert, A., Büyükinan, M., Pirgon, M.O., Kurku, H., Yılmaz, H, Odabaş, D.(2023). Left and right ventricular function by echocardiography, tissue doppler imaging, carotid intima media thickness, and asymmetric dimethylarginine levels in female adolescents with vitamin D deficiency. Cardiology in The Young. 1-8. doi: 10.1017/S1047951123001257. PMID: 37226488.