Effect of alpha-blocker use on morbidity and lower urinary tract symptoms in patients undergoing transrectal ultrasound-guided prostate biopsy

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dc.authorid0000-0002-1797-0877en_US
dc.contributor.authorSalar, Remzi
dc.contributor.authorErbay, Güven
dc.date.accessioned2022-01-20T13:02:08Z
dc.date.available2022-01-20T13:02:08Z
dc.date.issued2021en_US
dc.departmentKMÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS:000740959200001 PubMed ID34965804en_US
dc.description.abstractObjective: To evaluate voiding dysfunction and morbidity after transrectal ultrasound (TRUS)-guided prostate biopsy and to investigate whether pre-intervention alpha-blocker treatment had any effect on morbidity and voiding dysfunction. Material and methods: The study included 197 consecutive patients who underwent TRUS-guided prostate biopsy between January 2014 and January 2018. The patients were divided into two groups, those receiving alpha-blocker (silodosin) and those not receiving alpha-blocker treatment before the procedure (controls). All patients were evaluated before and one week after the procedure with the International Prostate Symptom Score (IPSS), measurements of maximum flow rate (Q(max)), post-void residual urine volume (PVR) and prostate volume, and procedure-related complications were also recorded. All analyzed parameters were compared by within-group and between-group evaluations. Results: There was no significant difference between the two groups in terms of IPSS, Q(max) and prostate volume values before biopsy. In the follow-up evaluation performed on the seventh day after biopsy, IPSS, PVR and prostate volume were found to be increased, whereas Q(max) was decreased in the control group (p<0.05). In the silodosin group, an increase in prostate volume was observed, but there were no significant changes in IPSS, Qmax and PVR values. Acute urinary retention (AUR) after the biopsy procedure developed in two patients (2%) in the silodosin group, and in nine patients (9.1%) in the control group (p =0.02). No significant difference was found between the two groups in terms of biopsy-related complications, except for AUR. Conclusion: We believe that alpha-blocker treatment initiated before biopsy may be advantageous in preventing voiding dysfunction that may develop after the procedure.en_US
dc.identifier.citationSalar, R., Erbay, G.(2021) Effect of alpha-blocker use on morbidity and lower urinary tract symptoms in patients undergoing transrectal ultrasound-guided prostate biopsy. Urologia Journal. doi:10.1177/03915603211038344en_US
dc.identifier.doi10.1177/03915603211038344
dc.identifier.issn0391-5603
dc.identifier.issn1724-6075
dc.identifier.pmid34965804
dc.identifier.urihttps://doi.org/10.1177/03915603211038344
dc.identifier.urihttps://hdl.handle.net/11492/5913
dc.identifier.wosWOS:000740959200001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Sceince
dc.indekslendigikaynakPubMed
dc.institutionauthorErbay, Güven
dc.language.isoen
dc.publisherSAGE Publications Ltden_US
dc.relation.journalUrologia Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAlpha-Blockersen_US
dc.subjectComplicationsen_US
dc.subjectLower Urinary Tract Symptomsen_US
dc.subjectTrus-Guided Prostate Biopsyen_US
dc.titleEffect of alpha-blocker use on morbidity and lower urinary tract symptoms in patients undergoing transrectal ultrasound-guided prostate biopsyen_US
dc.typeArticle

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