Molecular investigation of the effect of weightlifting training on helper T cell subsets in female weightlifting athletes: an immune profiling panel

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dc.authoridKuccukturk, Serkan/0000-0001-8445-666X
dc.authoridKaraselek, Mehmet Ali/0000-0003-3201-8945
dc.authoridDURAN, TUGCE/0000-0002-7353-4527
dc.contributor.authorDuran, Tugce
dc.contributor.authorKaraselek, Mehmet A.
dc.contributor.authorKuccukturk, Serkan
dc.date.accessioned2024-01-22T12:22:24Z
dc.date.available2024-01-22T12:22:24Z
dc.date.issued2023
dc.departmentKMÜen_US
dc.description.abstractBACKGROUND: In this study, it was aimed to molecularly investigate the changes in the helper T (Th) cell subgroups of intense weightlifting training. For this purpose, transcription factor and cytokine expressions of Th1, Th2, Th17, and regulator T cell (Treg) cells were evaluated.METHODS: Eight elite weightlifting athletes were included in the study. Within the scope of the study, transcription factor and cytokine expressions of Th cell subgroups were evaluated by real-time polymerase chain reaction (qPCR) method before training, after intense training with 90-100% capacity, and after 120 minutes of rest from training.RESULTS: As a result of the study, when the pre-training and post-training expressions were compared, an increase in Th1 and Th2 cell factors and a decrease in Th17 and Treg cell-related expressions were detected. These changes were statistically significant (P<0.05). The changes in expressions after training and after 120 minutes of rest were not statistically significant (P>0.05).CONCLUSIONS: Changes have been detected in Th cell subgroups due to intense weightlifting training, and these changes are the first study conducted with female weightlifters.en_US
dc.description.sponsorshipNecmettin Erbakan University Scientific Research Projects Coordinator [221218009]en_US
dc.description.sponsorshipThis research was funded by a grant from Necmettin Erbakan University Scientific Research Projects Coordinator with project number 221218009.en_US
dc.identifier.doi10.23736/S0022-4707.23.15001-8
dc.identifier.endpage1234en_US
dc.identifier.issn0022-4707
dc.identifier.issn1827-1928
dc.identifier.issue11en_US
dc.identifier.pmid37712925en_US
dc.identifier.pmid37712925
dc.identifier.scopus2-s2.0-85175270628
dc.identifier.scopusqualityQ2
dc.identifier.startpage1227en_US
dc.identifier.urihttps://doi.org/10.23736/S0022-4707.23.15001-8
dc.identifier.urihttps://hdl.handle.net/11492/7967
dc.identifier.volume63en_US
dc.identifier.wosWOS:001101377500013
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Sceince
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherEdizioni Minerva Medicaen_US
dc.relation.ispartofJournal of Sports Medicine and Physical Fitnessen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzkmusnmz
dc.subjectTh1 cellsen_US
dc.subjectTh2 cellsen_US
dc.subjectTh17 cellsen_US
dc.subjectRegulatory T-lymphocytesen_US
dc.subjectWeight liftingen_US
dc.titleMolecular investigation of the effect of weightlifting training on helper T cell subsets in female weightlifting athletes: an immune profiling panelen_US
dc.typeArticle

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