A perspective on the relationship between eveningness and schizophrenia through the mediation of vitamin D

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dc.contributor.authorKaraagac, Mustafa
dc.contributor.authorGica, Sakir
dc.date.accessioned2025-01-12T17:19:50Z
dc.date.available2025-01-12T17:19:50Z
dc.date.issued2024
dc.departmentKaramanoğlu Mehmetbey Üniversitesi
dc.description.abstractThis study investigates the relationship between chronotype and schizophrenia, focusing on the mediating role of vitamin D. A cross-sectional design was used, involving 51 schizophrenia patients and 53 healthy controls. Participants completed the Morningness-Eveningness Questionnaire (MEQ), and their vitamin D levels were measured. Schizophrenia patients exhibited significantly lower MEQ scores and vitamin D levels than controls. A mediation analysis revealed that vitamin D levels partially mediated the relationship between MEQ scores and the presence of schizophrenia. Lower MEQ scores, indicating an evening chronotype, were associated with reduced vitamin D levels, which, in turn, correlated with an increased likelihood of schizophrenia. However, no significant associations were found between vitamin D levels and symptom severity (measured by PANSS scores). These findings highlight the potential interplay between chronotype and vitamin D in schizophrenia, suggesting that addressing circadian disruptions and vitamin D deficiency could enhance therapeutic strategies for schizophrenia..
dc.identifier.doi10.1080/09291016.2024.2439932
dc.identifier.issn0929-1016
dc.identifier.issn1744-4179
dc.identifier.scopus2-s2.0-85212258491
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1080/09291016.2024.2439932
dc.identifier.urihttps://hdl.handle.net/11492/10230
dc.identifier.wosWOS:001379559500001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Sceince
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofBiological Rhythm Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20250111
dc.subjectChronotype
dc.subjectschizophrenia
dc.subjectvitamin D
dc.titleA perspective on the relationship between eveningness and schizophrenia through the mediation of vitamin D
dc.typeArticle

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