Candida Albicans Adhesion of New-generation Denture Base Materials

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dc.contributor.authorTemizci, Tugba
dc.contributor.authorDogan, Metin
dc.contributor.authorBozogullari, Hatice Nalan
dc.date.accessioned2025-01-12T17:13:11Z
dc.date.available2025-01-12T17:13:11Z
dc.date.issued2024
dc.departmentKaramanoğlu Mehmetbey Üniversitesi
dc.description.abstractABSTRACT Aim: Denture stomatitis, affecting approximately 65% of denture wearers, is a common symptom of oral candidiasis. With the advancement of digital dentistry, more contemporary materials are being used as denture base materials. The effect of Candida albicans adhesion on new-generation denture bases has not been investigated. This study aims to examine the adhesion of C. albicans to various dental polymers produced by different manufacturing methods and the effect of thermal cycling. Materials and Methods: A total of 60 disk samples (10×2 mm) were produced for microbiological tests. The samples were divided into two subgroups for each material group (n = 10). Three different denture base materials were produced using different techniques: 3 dimensional (3D) printed denture base resin, Formlabs (FL); conventional heat-polymerized acrylic, Meliodent (MD); and milled pre-polymerized polymethyl methacrylate (PMMA) resin disc manufactured using computer aided design/computer aided manufacturing (CAD/CAM) technology, Ivobase (IB). Before and after thermocycling, specimens were tested (5000 cycles, 5 °C/55 °C). The adhesion of C. albicans on the samples was examined under a microscope. Surface images of all groups were evaluated using scanning electron microscopy (SEM). Post-hoc Tukey test and two-way analysis of variance were used to analyze the data. Results: The CAD/CAM milled group and the 3D printed group showed significantly less C.albicans adhesion compared to the heat-polymerized acrylic resin. The effect of thermal cycling on microbial adhesion was found to be insignificant for all groups tested. Conclusion: Candida infections and associated denture stomatitis are less common in new-generation denture base materials compared to conventional heatpolymerized acrylic. To reduce microbial adhesion, denture base materials produced by 3D printing and milled by CAD/CAM could be a better choice.
dc.identifier.doi10.30733/std.2024.01762
dc.identifier.endpage116
dc.identifier.issn1017-6616
dc.identifier.issn2149-8059
dc.identifier.issue3
dc.identifier.startpage110
dc.identifier.trdizinid1265610
dc.identifier.urihttps://doi.org/10.30733/std.2024.01762
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1265610
dc.identifier.urihttps://hdl.handle.net/11492/9517
dc.identifier.volume40
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofSelçuk Tıp Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20250111
dc.subjectCandida albicans
dc.subject3D printing
dc.subjectdenture base
dc.subjectthermal cycling
dc.titleCandida Albicans Adhesion of New-generation Denture Base Materials
dc.typeArticle

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