Karaağaç, Mustafa2025-03-122025-03-122024(2024) Unexpected falls in schizophrenia: clozapine-induced negative myoclonus European Journal Of Therapeutıcs Volume:30 htt://10.58600/eurjther23412564-77842564-7040https://doi.org/10.58600/eurjther2341Myoclonus, characterized by sudden involuntary muscle contractions, can occur in a variety of conditions, including as a side effect of clozapine, which is used in the treatment-resistant schizophrenia. This case study describes a 48-year-old female patient who developed negative myoclonus, manifested by knee flexion and falls, after starting clozapine. Despite dose reduction and the addition of valproic acid, symptoms persisted, highlighting the dose-dependent nature of clozapine-induced myoclonus and the need for clinicians to recognise this risk.enClozapineMyoclonusSchizophreniaArticle306info:eu-repo/semantics/openAccessWOS:00141536250001710.58600/eurjther2341Q3