Duran, TugceKaraselek, Mehmet A.Kuccukturk, Serkan2024-01-222024-01-2220230022-47071827-1928https://doi.org/10.23736/S0022-4707.23.15001-8https://hdl.handle.net/11492/7967BACKGROUND: In this study, it was aimed to molecularly investigate the changes in the helper T (Th) cell subgroups of intense weightlifting training. For this purpose, transcription factor and cytokine expressions of Th1, Th2, Th17, and regulator T cell (Treg) cells were evaluated.METHODS: Eight elite weightlifting athletes were included in the study. Within the scope of the study, transcription factor and cytokine expressions of Th cell subgroups were evaluated by real-time polymerase chain reaction (qPCR) method before training, after intense training with 90-100% capacity, and after 120 minutes of rest from training.RESULTS: As a result of the study, when the pre-training and post-training expressions were compared, an increase in Th1 and Th2 cell factors and a decrease in Th17 and Treg cell-related expressions were detected. These changes were statistically significant (P<0.05). The changes in expressions after training and after 120 minutes of rest were not statistically significant (P>0.05).CONCLUSIONS: Changes have been detected in Th cell subgroups due to intense weightlifting training, and these changes are the first study conducted with female weightlifters.enTh1 cellsTh2 cellsTh17 cellsRegulatory T-lymphocytesWeight liftingArticle631112271234info:eu-repo/semantics/closedAccess2-s2.0-85175270628WOS:001101377500013377129253771292510.23736/S0022-4707.23.15001-8Q2Q3