Karamanoğlu Mehmetbey Üniversitesi Kurumsal Akademik Arşivi
DSpace@KMÜ, Karamanoğlu Mehmetbey Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Eco-friendly lead-free metal halide perovskites: progress and prospects in multifunctional applications
(Elsevier B.V., 2025) Mukhtar, Maria; Goud, Burragoni Sravanthi; Ali, Zeeshan; Shaid, Muhammad Waleed; Naz, Bushra; Ain, Qurat Ul; Assiri, Mohammed A.; Sönmezoğlu, Savaş; Rajpar, Altaf Hussain; Kim, Jae Hong; Aftab, Sikandar
Recently, metal halide perovskites have engrossed a lot of attraction in the field of developing optoelectronic technologies due to their special optical-electronic characteristics. The toxicity of lead (Pb) based perovskites has developed a major obstacle that restricts their widespread use, despite the fact that they seem to be rising stars in optoelectronic devices. To overcome this hurdle, Pb-free substitutive perovskites have earned growing interest because of their theoretically remarkable environment friendly optoelectronic properties besides compromising stability and enactment. They are not only gaining attention for applications in solar devices but their properties make them an ideal candidate for many other demanding applications. To elucidate the applicability of eco-friendly perovskites in numerous applications, the present article provides an extensive overview of current developments in eco-friendly perovskites in a range of contemporary applications outside of photovoltaics. An overview of these Pb-free perovskites' crystal structure and chemical variety is initially presented. For a number of purposes like artificial synapses, light-emitting diodes, resistive switching memory, photodetectors, and displays, a methodical review of lead-free perovskites is presented in this article. The demonstration of photocatalysis, radiation detection, imaging, sensors, thermoelectric and piezoelectric energy harvesting, and more is crucial. Pb-free perovskite future development prospects and challenges in the aforementioned fields are described, that are thought to be essential for accelerating the profitable adoption of above-mentioned cutting-edge technologies. © 2025 Elsevier B.V.
An efficient binary harris hawks optimization based on logical operators for wind turbine layout according to various wind scenarios
(Elsevier B.V., 2025) Beşkirli, Ayşe
Nowadays, with the demand for renewable energy the interest in wind energy is increasing day by day and the use of wind turbines is becoming widespread. In order to efficiently generate electricity from wind turbines, it is important that the turbines are correctly positioned on wind farms. In this study, a standard wind farm area of 2 km × 2 km was used for wind turbine layout. In addition, different from the literature, a 4 km × 4 km wind farm area was also created. Both wind farming areas were divided into 10 × 10 and 20 × 20 grids as in the literature. In addition, 25 × 25, 40 × 40 and 50 × 50 grids were also created. Thus, the wind farming area is divided into more grids and more flexible positioning of the turbines is aimed. There are three different case scenarios for the layout of the wind turbines. Case A has a constant wind speed of 12 m/s and unidirectional wind, while Case B has a constant wind speed of 12 m/s with a 36-directional 10° angle. Case C has variable wind speeds of 8, 12 and 17 m/s with a 36-directional 10° angle. The HHO algorithm was used to perform all these processes. However, since the wind turbine layout problem is binary, the HHO algorithm is adapted to binary with logic operators. These binary methods are called HHOAND and HHOXOR. The proposed methods achieved competitive results compared to other algorithms in the literature and performed well for all grid structures. Thus, it can be said that the proposed methods are effective for the wind turbine layout problem. © 2025 The Author(s)
Microbiome modulation as a novel therapeutic modality for anxiety disorders: a review of clinical trials
(Elsevier B.V., 2025) Adıgüzel, Emre; Yılmaz, Şemsi Gül; Atabilen, Büşra; Şeref, Betül
Anxiety disorders are one of the major conditions in psychiatry characterized by symptoms such as worry, social and performance fears, unexpected and/or triggered panic attacks, anticipatory anxiety, and avoidance behaviors. Recent developments have drawn attention to the putative involvement of peripheral systems in the control of anxiety, and the gut microbiota has come to light as an emerging peripheral target for anxiety. The relationship between the gut-brain axis, a bidirectional communication network between the central nervous system (CNS) and enteric nervous system (ENS), and anxiety has been the subject of some recent studies. Therefore, this systematic review analyzed clinical trials evaluating the potential of microbiome modulation methods in mitigating and ameliorating anxiety disorders. Clinical studies on probiotic, prebiotic, synbiotic supplements, dietary interventions, and fecal microbiota transplantation in anxiety disorders were screened. All of the studies examined the effects of probiotic intervention. One of these studies compared a prebiotic-rich diet with probiotic supplementation. Longitudinal analyses showed that the probiotic intervention alleviated anxiety. However, most of the controlled studies reported that the probiotic intervention did not make a difference compared to placebo. Thus, the current findings suggest that it is too early to consider the promising role of microbiome modulation in the treatment of anxiety disorders. However, it is obvious that more clinical research is needed to clarify issues such as probiotic strains, prebiotic types, and their doses that may be effective on anxiety disorders. © 2025 Elsevier B.V.
A fluorescent chemoprobe based on carbazole for hypochlorite with fast response: design and its applications in test strips, water samples and living cells
(Elsevier B.V., 2025) Savran, Tahir; Karuk, Elmas; Şükriye Nihan; Arslan, Fatma Nur; Sadi, Gökhan
Hypochlorite (ClO−) has been widely used as the main component of cleaning agents, and is also used in the treatment of disinfect water. The concentration of ClO− is critical for living organisms andthe environment. Hence, it is essential to develop reliable, sensitive and user-friendly molecular sensors to determine ClO−. In this context, the synthesized probe 2,4-di-tert-butyl-6-((E)-(((E)-(9-pentyl-9H-carbazol-3-yl)methylene) hydrazono) methyl) phenol (TBCP) can detect ClO− with rapid response (1 min), low detection limit (0.28 µM) and high sensitivity. Also, the sensor is utilized at wide pH range (4–10) for the determination of ClO−. TBCP showed outstanding selectivity for ClO− over other competing analytes via a fluorescent response change from colorless to orange, and its response mechanism was based on a deprotonation phenomenon. The ClO− level was successfully determined by TBCP on test kits, cotton swabs and in real samples. Fluorescent bio-imaging of ClO− in HEPG2 cells was also carried out in the presence of TBCP. Furthermore, DFT calculations were performed successfully for TBCP and TBCP + ClO− complex. © 2025 Elsevier B.V.
Constraints on the higgs boson self-coupling from the combination of single and double higgs boson production in proton-proton collisions at √s=13 tev
(Elsevier, 2025) Hayrapetyan, A; Tumasyan, A.; Adam, W.; Andrejkovic, J. W.; Bergauer, T.; Chatterjee, S.; Sağır, Sinan
The Higgs boson (H) trilinear self-coupling, lambda(3), is constrained via its measured properties and limits on the HH pair production using the proton-proton collision data collected by the CMS experiment at root s = 13 TeV. The combination of event categories enriched in single-H and HH events is used to measure k(lambda), defined as the value of lambda(3) normalized to its standard model prediction, while simultaneously constraining the Higgs boson couplings to fermions and vector bosons. Values of k(lambda) outside the interval -1.2 < k(lambda) < 7.5 are excluded at 2 sigma confidence level, which is compatible with the expected range of -2.0< k(lambda) < 7.7 under the assumption that all other Higgs boson couplings are equal to their standard model predicted values. Relaxing the assumption on the Higgs couplings to fermions and vector bosons the observed (expected) k(lambda) interval is constrained to be within -1.4 < k(lambda) < 7.8 (-2.3 < k(lambda) < 7.8) at 2 sigma confidence level.
