Yazar "Gumus, Numan Emre" seçeneğine göre listele

Listeleniyor 1 - 1 / 1
  • [ X ]
    Öğe
    A dual-responsive fluorescent sensor for selective detection of cyanide ions and histamine via distinct mechanisms in food samples
    (Elsevier Inc., 2025) Gokbel, Fuat; Eczacioglu, Numan; Gumus, Numan Emre; Aydin, Ziya
    Ensuring food safety requires rapid, sensitive detection of toxic contaminants like cyanide ions and spoilage markers like biogenic amines (BAs). Here, we present FZ-3 (combining 2,3,3-trimethyl-1-propyl-3H-indole-1-ium iodide with a pyridine moiety), a novel dual-sensitive fluorescent sensor that selectively detects cyanide ions (CN−) and histamine (His) through distinct reaction mechanisms. FZ-3 combines an indolium moiety for cyanide ions recognition via nucleophilic addition and, with a chloropyridine unit for His sensing via substitution. With minimal interference from other ions/biogenic amines, the sensor exhibits a turn-on response for CN− ions at 414 nm, while for His it enhances emission with a turn-on response at 463 nm. It demonstrates excellent sensitivity with detection limits of 1.08 μM for CN− and 2.80 μM for His, surpassing many existing single-analyte detection systems. FZ-3's efficacy was validated in food matrices by cyanide ions quantification in bitter almonds (recovery: 85.9–100.8 %) and sprouting potatoes (recovery: 85.4–103.9 %) and His detection in fresh/spoiled anchovies (recovery: 81.4–102.5 %), demonstrating correlation with spoilage levels. Notably, FZ-3 operates at physiological pH (3.9–8.0), requires <20 min for analysis, and surpasses conventional methods in cost, speed, and simplicity. This work advances dual-analyte sensing platforms for real-time food quality monitoring, offering a practical tool for both industrial and regulatory applications. © 2025 Elsevier B.V.