Yazar "Karaburgu, Sulbiye" seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • Küçük Resim
    Öğe
    Current perspective on diabetes mellitus in clinical sciences
    (Nobel Tıp Bookstores, 30/09/2023) Alp, Harun; Sahin, Ali; Karabaglı, Pınar; Karaburgu, Sulbiye; Yılmaz Sanal, Burcu; Yuksel, Emine Berrin; et al.; Alp, Harun; Rağbetli, Murat Çetin; Koksoy, Hale
    Diabetes Mellitus (DM) receives significant attention from most scientists due to being a major global public health threat. Diabetes is considered one of the leading causes of death due to its micro and macrovascular complications. This insidious killer is estimated to reach a staggering number of 578 million (700 million by 2045) cases by 2030. In this book, utilizing the disciplines of clinical sciences, various contemporary topics related to diabetes are extensively discussed. These include the classification of diabetes, underlying causes, epidemiology, pathogenesis, impact on sexual functions, association with cancer, clinical manifestations, diagnostic methods, complications, and treatment options. Furthermore, intriguing and current subjects such as "antidiabetic phytotherapy" and "the relationship between oral health and diabetes" are also covered. By doing so, readers will acquire comprehensive and detailed knowledge about the clinical management of diabetes. Thus, this book not only serves those who seek to understand the scientific aspects of diabetes but also proves to be a valuable resource for healthcare professionals, researchers, and students in a clinical setting. We believe that this book will contribute to understanding the complexity of diabetes and provide beneficial solutions while shedding light on future studies.
  • Küçük Resim
    Öğe
    Effect of hypothalamic adrenal axis and thyroid function alterations on prognosis of critically Ill COVID-19 Patients
    (Galenos Publ House, 2024) Korkusuz, Muhammet; Karaburgu, Sulbiye; Et ,Tayfun; Yarımoğlu, Rafet; Kumru, Nuh
    Aim: The aim of this study was to evaluate the effect of changes in adrenal, and thyroid functions on the prognosis of Coronavirus disease-2019 (COVID-19) patients admitted to the intensive care unit (ICU). Materials and Methods: This was a retrospective evaluation that included COVID-19 patients requiring ICU admission. Serum cortisol, adrenocorticotrophic hormone (ACTH), thyroid-stimulating hormone (TSH), free thyroxine (fT4) and triiodothyronine (fT3) levels were measured on admission and two more times during the hospitalization. Routine biochemistry, hemogram, C-reactive protein, procalcitonin, fibrinogen and D-dimer levels were also measured, along with hormones. All-cause mortality during ICU stay, inotropic drug and mechanical ventilation needs, and duration of hospitalization were recorded for each patient. Euthyroid sick syndrome (ESS) and hypocortisolism rates were determined. Deceased and surviving patients were compared in terms of hormone values, and logistic regression to determine independent associates of mortality was performed. Results: Overall, 124 patients (58% male, mean age 70.7 +/- 11.3 years) were included. During the ICU stay, both fT3 and fT4, but not TSH, showed a statistically significant decrease compared to admission values. Serum cortisol and ACTH values increased compared to admission values, but this increase was not significant. ESS was present in 89.5% of the patients. Two-thirds of the patients died in ICU. Serum fT3 values were significantly lower among decedents compared to survivors. Hypocortisolism was detected in 20.1% of the patients. Only the fT3 level could independently and significantly predict all-cause mortality. Conclusion: ESS was almost universal among critically ill COVID-19 patients. Serum fT3, but not other thyroid or adrenal hormones, could significantly predict all-cause mortality.
  • [ X ]
    Öğe
    Effects of high-intensity interval training program on pituartry function in basketball players: a randomized controlled trial
    (Frontiers Media Sa, 2023) Soslu, Recep; Uysal, Abdullah; Devrilmez, Meltem; Can cuvalcioglu, Ismail; Dogan, Ali Ahmet; Karaburgu, Sulbiye
    The aim of the study was to determine how the short high-interval training program affects cortisol levels in basketball players. A total of 27 male basketball players volunteered for the study and were randomly assigned to one of two groups: Control Group (CG) (n = 13, mean age; 20,56 +/- 1,45 years, mean height; 184,53 +/- 6,65 cm) and Experimental Group (EG) (n = 14, mean age; 20,71 +/- 2,12 years, mean height; 86,51 +/- 8,21 cm). The experimental group received a 7-week interval training program. Blood samples were taken at the beginning and end of the study. Cortisol, Adrenocorticotropic Hormone, Triiodothyronine, Tetraiodothyronine, Parathyroid Hormone, Thyroid Stimulating Hormone, Insulin, and Glucose levels were measured of the EG and CG. To test the differences between groups and compare the effects of pre and post-intervention, a two-way ANOVA for repeated measures was used. Consequently, the post-test levels of TSH, PTH, and ACTH in the exercise group showed a significant difference when compared to the pre-test values (p = 0.000). Moreover, the post-test levels of Glucose, Cholesterol, Triglyceride, HDL, and Mg in the exercise group showed statistical significance when compared to the pre-test values (p = 0.000). Significant differences were seen in the post-test PTH and ACTH levels of the control group when compared to the pre-test values (p = 0.000). Furthermore, the exercise group showed significant differences in post-test values for HDL and Cholesterol compared to the pre-test (p = 0.000). In addition, when comparing the post-test values and pre-test values of both the exercise group and the control group, it was found that all parameters, with the exception of Ca, exhibited substantial differences in favor of the exercise group. It may be claimed that the implementation of interval training has favorable outcomes on pituitary function parameters. Additionally, the regulation of energy consumption during exercise is favourably influenced, along with the reduction of physiological stress resulting from prolonged exercise.