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  • Küçük Resim
    Öğe
    Current compherensive approach to Covid-19
    (Duvar Kitapevi, 1/06/2022) Koksoy, Hale; Rağbetli, Murat Çetin; Alp, Harun; Ecesoy, Hilal; Basaran, Aynur; Kaya, Aysenur; Sahin, Ali; Bekci, Taha Tahir; Yesildag, Ahmet; Ecesoy, Volkan; Kocabas, Rahim; Karaburgu, Sülbiye; Ay, Mehmet Emre; Dulger, Ozlem; Osmanoglu, Omer Usame; Serin, Aliye Nigar; Ragbetli, Cennet; Kose, Fulya; Atik, Dilek; Kılıc, Nuray; Mustu, Mehmet; Alkan, Gulsum; Arıcı, Hasan; Alp, Harun; Rağbetli, Murat Çetin; Koksoy, Hale
    This book, prepared by our Karamanoglu Mehmetbey and other faculty members by adding their current experiences during the pandemic process, is one of the leading scientific publications about the COVID-19 pandemic.
  • Küçük Resim
    Öğe
    Current multidisciplinary approach to diabetes mellitus occurrence mechanism
    (Nobel Tıp Bookstores, 30/09/2023) Rağbetli, Murat Çetin; Kaya, Aysenur; Keskin, Seda; Kıran, Tugba Raika; Karabulut Bay, Aysun; Unal, Mustafa; Uguz, A. Cihangir; Kocaman, Süheyla; Dasdelen, Dervis; Koksoy, Hale; Kocabas, Rahim; Ecesoy, Volkan; Arıcı, Hasan; Osmanoglu, Omer Usame; Irgat İncedal, Serap; Gumus, Hale Hatice; Alp, Harun; Rağbetli, Murat Çetin; Koksoy, Hale
    This book aims to provide a current and comprehensive perspective on Diabetes mellitus, a valuable subject in the field of basic sciences. Diabetes mellitus is a chronic disease that affects millions of people worldwide and has become an increasingly serious health problem. This book examines the underlying mechanisms and causes of diabetes using the disciplines of basic sciences. The content of the book begins with fundamental information such as the definition, classification, histopathological mechanisms, and epidemiology of diabetes. It also includes interesting sections on current technologies and the use of artificial intelligence in the field of diabetes. Additionally, the book extensively discusses how genetic predisposition, environmental factors, and lifestyle choices affect the risk of diabetes. This comprehensive evaluation of diabetes from the perspective of basic sciences provides important insights into the development and progression of the disease.
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    Öğe
    The potential protective effects of melatonin and omega-3 on the male rat optic nerve exposed to 900?MHz electromagnetic radiation during the prenatal period
    (Taylor & Francis Ltd, 2023) Tuefekci, Kiymet Kuebra; Kaplan, Arife Ahsen; Kaya, Aysenur; Alrafiah, Aziza; Altun, Gamze; Aktas, Abit
    Background: Due to children and adolescents' widespread use of electronic devices, researchers have focused on pre-and early postnatal electromagnetic field (EMF) exposure. However, little is known about the effects of EMF exposure on the optic nerve. The aim of study was to investigate the changes occurring in the optic nerve and the protective effects of melatonin (mel) and omega 3 (?-3) in rats.Methods: Thirty-five pregnant rats were divided into seven groups, Cont, Sham, EMF, EMF + melatonin (EMF + Mel), EMF + ?3, Mel, and ?3. The EMF groups were exposed to 900 megahertz (MHz) EMF daily for two hours during pregnancy. After the experiment, the right optic nerve of each offspring rat was removed and fixed in glutaraldehyde. Thin and semi-thin sections were taken for electron microscopic and stereological analyses. Myelinated axon numbers, myelin sheath thicknesses, and axonal areas were estimated using stereological methods.Results: The groups had no significant differences regarding mean numbers of axons, mean axonal areas, or mean myelin sheath thicknesses (p > 0.05). Histological observations revealed impaired lamellae in the myelin sheath of most axons, and vacuolization was frequently observed between the myelin sheath and axon in the EMF-exposed group. The Mel and ?-3-treated EMF groups exhibited well-preserved myelinated nerve fibers and intact astrocytes and oligodendrocytes.Conclusions: At the ultrastructural level, Mel and ?3 exhibits a neuroprotective effect on the optic nerve exposed to prenatal EMF. The protective effects of these antioxidants on oligodendrocytes, which play an essential role in myelin formation in the central nervous system, now require detailed investigation.