Mühendislik Fakültesi, Biyomühendislik Bölümü,Kitap ve Kitap Bölümleri Koleksiyonu
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Öğe Nanotechnology in food and agriculture(Nova Science Publishers, Inc., 2020) Eyidoğan, F.; Bayraç, Ceren; Bayraç, Abdullah Tahir; Baloğlu, M.C.; Ünel, N.M.; Öktem, H.A.Due to their extraordinary properties, nanoparticles have enormous applications in different fields. Nanotechnology is an obstructive field and has a potential with developed methods to change the current scenario of the food and agricultural industry. Developments and innovations in nanotechnology like nanosensors, nanopesticides, nanofertilizers, nanoencapsulation, and active packaging, facilitated the transformations in food and agriculture sectors. In this chapter, the most recent applications of nanotechnology in food and agriculture and the safety issues of nanomaterials in processing and packaging are discussed. Nanotechnology exhibits promising potentials to be widely utilized in every aspect of food and agriculture. Therefore, the rapid progress of nanotechnology will be helpful to facilitate the development of agriculture and the food sector. © 2020 Nova Science Publishers, Inc. All rights reserved.Öğe Aptamers in medical diagnosis(Pan Stanford Publishing Pte. Ltd., 2016) Özalp, V.C.; Kavruk, M.; Dilek, O.; Bayraç, Abdullah TahirAptamers have been increasingly applied in biomedical field as a class of biorecognition elements that possess many advantages such as high specificity and binding affinity, easy synthesis, easy modification, small size, non-toxicity and good stability. Many diseases like cancer exhibit cellular aberrations at morphological and molecular levels. Medical diagnosis based on molecular features can be highly specific and extremely sensitive when proper recognition molecule and an efficient signal transduction system are employed. However, bioanalysis of human diseases at the molecular level is an extremely challenging field because effective probes to identify and recognize biomarkers of diseases are not readily available. Traditional bio-recognition molecule, antibody has been exploited to develop excellent diagnosis assays in many formats, but antibodies are insufficient to match the requirements of fast and portable biosensors for point-of-care applications, which are at high demand in pathogenic bacteria detection as well as other diseases like cancer. Aptamers are short single-stranded oligonucleotides, which can be selected from random combinatorial library by SELEX in vitro. This relatively new biorecognition agent has superior intrinsic characteristics for biosensor development. In this review, we first present major aptamer selection technologies and the main formats of biosensors, which were frequently employed in aptasensor development. Then, the current state of aptamers as applied to medical diagnosis was discussed for specifically cancer and pathogen diagnosis. Finally, an overview of aptamer-nanomaterials conjugates was presented in many applications such as diagnosis, bioimaging, and theranosticsÖğe Biyoremediyasyon(Palme, 2013) Thieman, William J.; Palladino, Micheal A.; Bayraç, Abdullah TahirÇevremiz alarm veren sıklıkta tehdit ediliyor. Soluduğumuz hava, içtiğimiz su ve beslenmek amacıyla bitkileri yetiştirmek için güvendiğimiz toprak insan aktivitelerinin doğrudan bir sonucu olarak kirlenmektedir. Ortalama bir Amerikalı günlük olarak yaklaşık 2.5 kg çöp üretmekte, bu kişi başına yılda 850 kg’dan fazlaya denk düşmektedir ve sonuç olarak her yıl toplam yaklaşık 250 milyon ton atık maddeye neden olmaktadır. Bu atıkların sadece yaklaşık 1/3’ü (yaklaşık 83 milyon ton) geri dönüştürülür veya kompoze edilir; geri kalanı çöp toplama alanlarına gider. Ancak ev atıkları sorunun kısmen küçük bir bölümüdür. Kimyasal döküntülerden olduğu kadar, endüstriyel üretim atıklarından oluşan kirlilik, ev ürünleri ve pestisitler çevre kirliliğine neden olurlar. Artan sayıdaki toksik kimyasallar dünya genelinde çevre sağlığına ve içinde yaşayan organizmalara ciddi tehlikeler oluşturmaktadır.
