Effect of MIND diet on oxidative stress markers in multiple sclerosis

dc.contributor.authorAtabilen, Büşra
dc.contributor.authorAcar özen, Pınar
dc.contributor.authorTuncer, Aslı
dc.contributor.authorPolat, Merve Banu
dc.contributor.authorPınar, Aslı
dc.contributor.authorAkdevelıoğlu, Yasemin
dc.date.accessioned2025-08-11T11:23:19Z
dc.date.available2025-08-11T11:23:19Z
dc.date.issuedSeptember 2025
dc.departmentKMÜ, Sağlık Bilimleri Fakültesi, Beslenme ve Diyetetik Bölümü
dc.description.abstractThe aim of this dietary intervention study is to evaluate the effect of the MIND diet on oxidative stress markers and nutritional status in patients with Multiple sclerosis (MS). Methods: The study was conducted on 30 participants aged of 20–45 who were diagnosed with Relapsing-remitting MS. After the initial evaluation, healthy nutrition recommendations were given to the participants through a MIND diet sample menu list for 8 weeks. At the end of the study, all measurements were repeated. Results: The mean score of MIND diet adherence questionnaire and serum total antioxidant status level increased significantly at the end of the eighth week (p < 0.001 and p < 0.05). Although the results were not significant, serum superoxide dismutase, catalase and glutathione peroxidase levels tended to increase. In females, there was a significant decrease in body weight, body mass index, waist circumference and total body bone-free lean mass at the end of the study (p < 0.05). In addition, mean daily protein intake and protein intake per kg increased significantly in males (p = 0.028 for both variables) and dietary fiber intake increased significantly (p = 0.047) in all participants. Conclusion: This study showed that the MIND diet may has positive effects on increasing the defense system against inflammation and oxidative stress.
dc.identifier.doi10.1016/j.msard.2025.106598
dc.identifier.issn2-s2.0-105009463022
dc.identifier.urihttps://www.doi.org/10.1016/j.msard.2025.106598
dc.identifier.urihttps://hdl.handle.net/11492/11000
dc.identifier.volume101
dc.indekslendigikaynakScopus
dc.institutionauthorAtabilen, Büşra
dc.institutionauthoridAtabilen, Büşra/0000-0002-8485-1763
dc.language.isoen
dc.publisherElsevier B.V.
dc.relation.ispartofMultiple Sclerosis and Related Disorders
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAnthropometric Measurements
dc.subjectAntioxidant Enzymes
dc.subjectMediterranean Diet
dc.subjectMind Diet
dc.subjectMultiple Sclerosis
dc.subjectOxidative Stress
dc.titleEffect of MIND diet on oxidative stress markers in multiple sclerosis
dc.typeArticle

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