Ultrasound-guided bilateral modified-thoracoabdominal nerve block through a perichondrial approach (M-TAPA) in patients undergoing laparoscopic cholecystectomy: A randomized double-blind controlled trial

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dc.authorid0000-0003-2804-9589en_US
dc.authorid0000-0001-5994-3861en_US
dc.authorid0000-0002-0111-3360en_US
dc.authorid0000-0003-2534-5243en_US
dc.authorid0000-0001-6890-3474en_US
dc.contributor.authorBilge, Ayşegül
dc.contributor.authorBaşaran, Betül
dc.contributor.authorEt, Tayfun
dc.contributor.authorKorkusuz, Muhammet
dc.contributor.authorToprak, Hatice
dc.contributor.authorYarımoğlu, Rafet
dc.contributor.authorKumru, Nuh
dc.date.accessioned2022-11-08T08:44:09Z
dc.date.available2022-11-08T08:44:09Z
dc.date.issued2022en_US
dc.departmentKMÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS:000876280900001 PubMed ID:36307755
dc.description.abstractBackground: Modified thoracoabdominal nerve block through the perichondrial approach (M-TAPA) is a new technique that provides effective analgesia of the anterior and lateral thoracoabdominal walls by administering local anesthesia only to the underside of the perichondral surface. The primary purpose of the present study was to investigate the postoperative analgesic efficacy of M-TAPA block performed before surgery in patients undergoing laparoscopic cholecystectomy (LC). Method: The present study was designed as a double-blind, randomized, controlled, prospective study. A total of 68 patients were included in the study. In group M-TAPA, M-TAPA block was performed bilaterally after the induction of general anesthesia. No block was performed on the group control. The postoperative pain scores, analgesic use in the first 24 h, antiemetic consumption, sedation, postoperative nausea and vomiting (PONV), and Quality of Recovery-40 (QoR-40) scores were recorded. Results: Pain scores were significantly lower in group M-TAPA than in the group control, both during resting and motion at all times (p < 0.001 at each time point). The total amount of tramadol consumed in the first 24 h was lower in group M-TAPA [median 100 mg, min-max (0-200)] than in the group control (P < 0.001). Postoperative median QoR-40 scores were higher in group M-TAPA compared with the group control (P < 0.001). There were no differences between the groups in terms of other results. Conclusion: After the LC surgery, ultrasound-guided M-TAPA block reduced postoperative pain scores and tramadol consumption effectively. It was observed that the quality of recovery was also higher because QoR-40 scores were higher.en_US
dc.identifier.citationBilge, A., Başaran, B., Et, T., Korkusuz, M., Yarımoğlu, R., Toprak, H., & Kumru, N. (2022). Ultrasound-guided bilateral modified-thoracoabdominal nerve block through a perichondrial approach (M-TAPA) in patients undergoing laparoscopic cholecystectomy: A randomized double-blind controlled trial. BMC Anesthesiology, 22(1) doi:10.1186/s12871-022-01866-4en_US
dc.identifier.doi10.1186/s12871-022-01866-4
dc.identifier.issn1471-2253
dc.identifier.issue1en_US
dc.identifier.pmid36307755
dc.identifier.scopus2-s2.0-85140744117
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1186/s12871-022-01866-4
dc.identifier.urihttps://hdl.handle.net/11492/6737
dc.identifier.volume22en_US
dc.identifier.wosWOS:000876280900001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Sceince
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorBilge, Ayşegül
dc.institutionauthorBaşaran, Betül
dc.institutionauthorEt, Tayfun
dc.institutionauthorKorkusuz, Muhammet
dc.institutionauthorToprak, Hatice
dc.language.isoen
dc.publisherBioMed Central Ltden_US
dc.relation.journalBMC Anesthesiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnalgesiaen_US
dc.subjectLaparoscopic Cholecystectomyen_US
dc.subjectNerve Blocken_US
dc.subjectPain Managementen_US
dc.subjectPostoperative Painen_US
dc.subjectUltrasonographyen_US
dc.titleUltrasound-guided bilateral modified-thoracoabdominal nerve block through a perichondrial approach (M-TAPA) in patients undergoing laparoscopic cholecystectomy: A randomized double-blind controlled trialen_US
dc.typeArticle

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