The relationship between fibromyalgianess and clinical features, disease activity in patients with systemic lupus erythematosus

Basit Öğe Kaydı
dc.contributor.authorVarman, Büşra
dc.contributor.authorParlak, Selman
dc.contributor.authorEcesoy, Hilal
dc.date.accessioned2025-03-04T07:58:14Z
dc.date.available2025-03-04T07:58:14Z
dc.date.issued2025
dc.departmentKMÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractIntroduction: Fibromyalgia (FM) is a chronic syndrome characterised by widespread pain, fatigue, and symptoms such as sleep disturbances, cognitive impairment, and mood disorders. FM prevalence is notably higher among systemic lupus erythematosus (SLE) patients compared with the general population, often leading to diagnostic challenges. Misinterpreting FM as SLE activity can result in overtreatment. This study aimed to evaluate fibromyalgianess and its relationship with the clinical and immunological characteristics of SLE patients using comprehensive scoring methods for better diagnostic accuracy. Materials and Methods: This cross-sectional study included 50 SLE patients meeting the 2019 EULAR/ACR classification criteria. Patients with coexisting autoimmune diseases or severe systemic conditions were excluded. Clinical data, SLEDAI scores, and fibromyalgianess severity were assessed using the Polysymptomatic Distress Scale (PSDS). Patients were categorised into groups based on fibromyalgia diagnostic criteria: widespread pain and SLE-FM. Statistical analysis was performed using SPSS, with p < 0.05 considered significant. Results: Among 50 patients (45 female, 5 male; mean age 42.04 +/- 12.5), 24% had fibromyalgianess, and 18% experienced widespread pain. Female patients exhibited significantly higher PSDS scores (p < 0.05). While NSAID use was associated with increased PSDS scores (p < 0.001), no significant relationship was found between fibromyalgianess and SLEDAI scores or organ involvement. Conclusion: Fibromyalgianess in SLE patients primarily reflects heightened pain sensitivity and symptom severity rather than disease activity. Incorporating fibromyalgianess assessment into routine SLE management may prevent diagnostic and therapeutic pitfalls and improve treatment outcomes. Multidisciplinary approaches, including pharmacological and non-pharmacological strategies, are essential for effective care.
dc.identifier.citationVarman, B., Parlak, S., & Ecesoy, H. (2025). The relationship between fibromyalgianess and clinical features, disease activity in patients with systemic lupus erythematosus. Musculoskeletal Care, 23(1), e70052. https://doi.org/10.1002/msc.70052
dc.identifier.doi10.1002/msc.70052
dc.identifier.issn1478-2189
dc.identifier.issn1557-0681
dc.identifier.issue1
dc.identifier.pmid39812620
dc.identifier.urihttps://doi.org/10.1002/msc.70052
dc.identifier.urihttps://hdl.handle.net/11492/10577
dc.identifier.volume23
dc.identifier.wosWOS:001397933100001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.indekslendigikaynakScopus
dc.institutionauthorEcesoy, Hilal
dc.institutionauthoridEcesoy, Hilal/0000-0001-9274-168X
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofMusculoskeletal Care
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectFibromyalgianess
dc.subjectPolysymptomatic Distress Scale
dc.subjectSystemic Lupus Erythematosus
dc.titleThe relationship between fibromyalgianess and clinical features, disease activity in patients with systemic lupus erythematosus
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Dahili Tıp Bilimleri Bölümü, Makale Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu